8 results
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Warm vs Cold Autoimmune ... Findings: Coombs positive ... Mycoplasma, HIV, EBV ... Findings: Coombs Positive ... #hematology #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... dehydrogenase • Positive ... - Mycoplasma, EBV ... #hematology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... workup, including BM ... • Nonmalignant hematologic ... hemolysis, deficiency anemia ... infarction, Severe trauma
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... Anticonvulsants - Gold ... Parvovirus B19 - EBV ... Epstein-Barr virus (EBV ... #oncology #hematology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
(COVID19, CMV/EBV ... - Seizures: Trauma ... Illness Myopathy (ICU ... Electrolytes: hypo- phos, kalemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
practices that could ... changes), high MCV anemia ... or if a primary hematologic ... When do you do a BM ... Causes #Workup #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Weight loss • Anemia ... Immune hemolytic anemia ... and usually CD15 positive ... classification #hematology
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
(@MarkRamzyDO, EM ... Hamilton, MD (EM ... Case A 39-year-old ... suffered no head trauma ... Pertinent positives