2548 results
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Adjustments due to Risk ... Metformin #Renal #Dosing ... #Dose #Pharmacology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... binds magnesium • Dosing ... and calcium • Dosing ... sodium intake; risk ... #medications #pharmacology
Warfarin - INR Goals, Initial Dosing and Bridging

Mechanical Mitral Valve Replacement 2.5-3.5 
Other Valve Replacement 2-3
Goals, Initial Dosing ... appropriate warfarin dosing ... high bleeding risks ... Goals #Targets #Dosing ... Bridging #Initiation #Pharmacology
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH)
UFH:
 • Advantages: 
    -
Unknown Optimal dosing ... data on whether risk ... Unfractionated #pharmacology
Rasburicase Pharmacology Summary

Recombinant urate oxidase from saccharomyces
Immediate onset of action
Dosing:
 - Package insert: 0.2 mg/kg IV
Rasburicase Pharmacology ... onset of action Dosing ... until no longer at risk ... #Rasburicase #Pharmacology
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy

• No previous history of
complications BUT high-risk ... Aspirin #LWMH #Dosing ... #Pharmacology
Daliresp (Roflumilast) 
Indication: Reduce risk of COPD exacerbations 
Drug Class: Selective Phosphodiesterase-4 (PDE4) Inhibitor 
GOLD 2019
Indication: Reduce risk ... Eosinophils < 100 Dosing ... to reduce the risk ... #Indications #Pharmacology
While certain drugs are used to control seizures, others can induce seizures in patients without a
The risk of drug-induced ... with potential risk ... The risk of seizure ... /or preventive dosing ... #Pharmacology #Lower
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
carrying only a low risk ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
oral suspension DOSING ... they carry the risk ... #Hyperkalemia #Pharmacology