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diagnosis management rheumatology causes comparison msk physicalexam treatment algorithm all apml aspergillus betadglucan biomarkers classification cppd differentiation effusions erythematosus extremity
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential ... Fever/Chills/Joint ... Reactive Syndrome - Acute ... rheumatic fever ... Effusions: - Hematologic
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Schema for Standard-Risk ... Acute Lymphoblastic ... Cytarabine #ALL #Acute ... Treatment #timeline #oncology ... #pediatrics #peds
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm Congenital Anomaly / Disorder: •
Infancy (SUDI) - Differential ... Accidental* Other: • Acute ... 80% of SUDI • Risk ... Algorithm #Causes #Peds ... #Pediatrics
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
Acute CPP Crystal ... inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... #Comparison #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Attempt if high risk ... : • Common: fever ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... drug failure • Risk ... management #treatment #rheumatology
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... Arthritis • Gout ... injury • DVT (Risks ... Immobilization) • Acute ... pain/swelling - Fever
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Classification: • Acute ... permanent alopecia Differential ... to: Arthritis, Fever ... Thrombosis highest risk
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) in hematologic ... useful in high risk ... BAL GM does not differentiate ... post-2010 almost never ... or GVHD (leaky gut
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... • Dyspnea • Fever ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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