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diagnosis management hematology betadglucan fungal galactomannan latenttb rheumatology tb tuberculosis abscess als amyotrophic apml aspergillus bacterial biomarkers brain cardiology causes
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... characteristic features Clinical ... TB: • Fever • ... Tuberculosis Treatment ... Inhibitor: • Risk
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... characteristic features Clinical ... TB: • Fever • ... Tuberculosis Treatment ... Inhibitor: • Risk
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Attempt if high risk ... Subacute-Acute: • Common: fever ... initiation • Differential ... Diagnosis: Infection ... management #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... ) B symptoms → fevers ... Complications: 1) Infection ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology
Spontaneous Bacterial Peritonitis DIAGNOSTICS Paracentesis: • Calculate absolute PMN count (total WBC x PMN %) • Correct
Treat if other signs ... (fever, abdominal ... small study, low-risk ... ß-blockers due to ↑ risk ... SBP • PPIs = ↑ risk
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... pneumonia • DM risk ... Lung Abscess - Clinical ... : • 80% have fever ... Intervention: - Fevers
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Excessive glutamate activity ... Dysphagia- increased risk ... conditions listed in differential ... diagnosis column Treatment ... by decreasing activity
Pocket Hematoma after Pacemaker Placement A rare, but can't-miss complication from pacemaker placement. Low incidence (1-9%) overall,
but increased risk ... walled-off area at risk ... is a 6x risk compared ... Heparin increases risk ... use has a LOWER risk
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... Diagnose concomitant infection ... drug failure • Risk
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
invasive fungal infection ... cut-offs defined in clinical ... useful in high risk ... BAL GM does not differentiate ... admin of mold-active
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