18 results
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
MUCORMYCOSIS • Risk ... has five major clinical ... • Cough, fever ... stain of clinical ... Encapsulated yeast • At risk
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) ... in hematologic ... cut-offs defined in clinical ... useful in high risk ... BAL GM does not differentiate
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... pneumonia • DM risk ... Lung Abscess - Clinical ... : • 80% have fever ... Prevotella • Fungal
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... (NTM) • Fungal ... characteristic features Clinical ... Active TB: • Fever ... Inhibitor: • Risk
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Attempt if high risk ... Subacute-Acute: • Common: fever ... initiation • Differential ... Diagnosis: Infection ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... ) B symptoms → fevers ... Complications: 1) Infection ... chemotherapy for low-risk ... Leukemia #oncology #hematology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... (NTM) • Fungal ... characteristic features Clinical ... Active TB: • Fever ... Inhibitor: • Risk
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... Pseudomonas FUNGAL ... • CT: Halo sign ... Pneumonia: • Risk
Debridement and Management of Prosthetic Joint Infection (PJI)
Duration of symptoms <3 weeks OR  <30 days
Staphylococci: 24wk for knees ... DDIs/AEs) - Fungus ... whether benefit > risk ... - Never “lifelong ... #treatment #Debridement
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... Diagnose concomitant infection ... drug failure • Risk