16 results
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... noninflammatory Signs ... • Rheumatic fever ... • Lyme • Gout ... #Differential #
Pediatrics Sepsis Screening
SIGNS OF INFECTION?
 • Fever (>38C)
 • Hypothermia (<36C)
 • Cough/chest pain/respiratory distress
 •
Pediatrics Sepsis ... OF INFECTION? ... • Fever (>38C) ... RISK MEDICAL CONDITIONS ... • Other high-risk
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... swelling, significant pain ... drug failure • Risk
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Arthritis • Gout ... : • Infection: ... injury • DVT (Risks ... /swelling - Fever
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
onset of swelling, pain ... inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... #Comparison #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... 9) Unexplained fever ... , when infection ... including in children (pediatric ... erythematosus #rheumatology
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... • CT: Halo sign ... Pneumonia: • Risk ... AIDS #pulmonary #differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
invasive fungal infection ... useful in high risk ... BAL GM does not differentiate ... or GVHD (leaky gut ... Fungal #Biomarkers #BetaDGlucan
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Attempt if high risk ... Subacute-Acute: • Common: fever ... effusions, weight gain ... initiation • Differential ... Diagnosis: Infection
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
surfaces, Albumin, Infections ... useful in high risk ... in BAL does not differentiate ... or GVHD (leaky gut ... blood products #BetaDGlucan