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diagnosis management hematology oncology activetb betadglucan clinical comparison galactomannan gout infectiousdiseases joint latenttb lung peds pulmonary symptoms tb tuberculosis abscess
“Step by Step” – the new kid on the block – aims to risk stratify this
block – aims to risk ... investigations and treatments ... those patients at risk ... considered “low risk ... #Antibiotics #Risk
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... : Temperature rises ... Brucellosis Faget's Sign ... For every 1°F rise ... #Patterns #Differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... noninflammatory Signs ... Mycobacterial • Fungal ... • Rheumatic fever ... tuberculosis) • Fungi
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... surfaces - Infections ... useful in high risk ... BAL GM does not differentiate ... post-2010 almost never
Pediatrics Sepsis Screening SIGNS OF INFECTION? • Fever (>38C) • Hypothermia (<36C) • Cough/chest pain/respiratory distress •
Pediatrics Sepsis ... OF INFECTION? ... • Fever (>38C) ... RISK MEDICAL CONDITIONS ... • Other high-risk
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... pneumonia • DM risk ... : • 80% have fever ... Intervention: - Fevers ... Prevotella • Fungal
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... (NTM) • Fungal ... Active TB: • Fever ... Tuberculosis Treatment ... Inhibitor: • Risk
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... Pseudomonas FUNGAL ... • CT: Halo sign ... Pneumonia: • Risk
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Attempt if high risk ... Subacute-Acute: • Common: fever ... initiation • Differential ... Diagnosis: Infection
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Disorders: • Infection ... (tuberculosis, fungal ... infections) ... hypotension develops • Risk ... • Low-grade fever
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