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diagnosis management infectiousdiseases activetb betadglucan galactomannan hematology latenttb oncology pulmonary tb tuberculosis abscess addisons adrenal aids apml aspergillus autoimmune biomarkers
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... : Temperature rises ... Brucellosis Faget's Sign ... For every 1°F rise ... Brucellosis • Liver or lung
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... pneumonia • DM risk ... : • 80% have fever ... Prevotella • Fungal ... Abscess Differential
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... in HIV - Differential ... Pseudomonas FUNGAL ... • CT: Halo sign ... Pneumonia: • Risk
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... (NTM) • Fungal ... Active TB: • Fever ... Tuberculosis Treatment ... Inhibitor: • Risk
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
lymph nodes Risk ... (NTM) • Fungal ... Active TB: • Fever ... Tuberculosis Treatment ... Inhibitor: • Risk
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... surfaces - Infections ... useful in high risk ... BAL GM does not differentiate ... Clav (may be + as long
Primary Adrenal Insufficiency Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
(tuberculosis, fungal ... infections) ... Adrenals: • Lung ... hypotension develops • Risk ... • Low-grade fever
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Attempt if high risk ... Subacute-Acute: • Common: fever ... initiation • Differential ... Diagnosis: Infection
Debridement and Management of Prosthetic Joint Infection (PJI) Duration of symptoms <3 weeks OR <30 days
Staphylococci: 24wk for knees ... DDIs/AEs) - Fungus ... whether benefit > risk ... - Never “lifelong ... #treatment #Debridement
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
inflammatory response Risk ... forefoot, ankles, knees ... 12-24 Hours • Fever ... drug failure • Risk ... #rheumatology
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