11 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Pathophysiology ... Attempt if high risk ... Diagnosis: >3 symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Findings Risk ... Apolipoprotein E4 allele Risk ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Pathophysiology: ... Risk factors: age ... Treatment: anticholinergics ... #PhysicalExam #clinical ... #neurology #posture
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Pathogenesis and clinical ... Patients at Risk ... Constipation - MSK ... #diagnosis #pathophysiology ... #symptoms #signs
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... Risk Factors: ... overload) Other Symptoms ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Neurological symptoms ... Risk factors 3. ... epilepticus Treatment
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... • Depressive symptoms ... : The clinical ... syndrome of HAD ... dementia #AIDS #Neurology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Bone Groups at risk ... poor nutrition Clinical ... Psychiatric symptoms ... nonimmune hemolysis MSK ... vasculitis Treatment
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
MUCORMYCOSIS • Risk ... has five major clinical ... fungal stain of clinical ... Encapsulated yeast • At risk ... Aspergillosis Pathophysiology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... fasciculations Common Symptoms ... Dysphagia- increased risk ... diagnosis column Treatment ... Lateral #Sclerosis #neurology