16 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... Findings Risk ... Apolipoprotein E4 allele Risk ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... chemotherapy for low-risk ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... Attempt if high risk ... Diagnosis: >3 symptoms ... management #hematology #oncology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Pathogenesis and clinical ... Patients at Risk ... Constipation - MSK ... #diagnosis #pathophysiology ... #symptoms #signs
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... antibiotics TLS ... low Ca - q8 h TLS ... mg/dL or > 25 % rise ... #HemeOnc #Diagnosis
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... myopathies such as ... muscle fibers Risk ... Pitavastatin Risk ... IU/I • SAMS clinical
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
may cause severe clinical ... Risk Factors: ... overload) Other Symptoms ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
injection sites) ↑ Risk ... ♀, ↑Age, ESRD Pathophysiology ... Diagnosis: • Clinical ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Risk factors 3. ... edema visualized as ... epilepticus Treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... carries a variable risk ... factor (GCSF) treatments ... and reducing the risk ... diagnosis #hematology #oncology