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pharmacology doac hematology anticoagulant dabigatran management noac coagulation cascade oral pathophysiology pt treatment abnormal absorption afib algorithm anatomy aptt atrial
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... for VTE - Dr. ... #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Clotting Time Warfarin ... Fondaparinux Rivaroxaban ... Apixaban, Edoxaban ... #Tests #Anticoagulation ... #Testing #Diagnosis
Coagulation Cascade - Actions of Anticoagulants • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin • Fondaparinux • Direct
Cascade - Actions of Anticoagulants ... Xa Inhibitors: Rivaroxaban ... , Apixaban, Edoxaban ... K Antagonists: Warfarin ... #anticoagulation
Choice of anticoagulant for treatment of pulmonary embolism • Malignancy - LMWH • To avoid parenteral
Choice of anticoagulant ... ; apixaban • Once ... ; edoxaban; VKA ... #decisionaid #vte ... #anticoagulation
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
Anticoagulants Common ... Reversal Agents - Warfarin ... (Praxbind) - Apixaban ... Betrixaban (Bevyxxa), Edoxaban ... (Lixiana), Rivaroxaban
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing Renal Dosing: Apixaban (25% renal clearance):
: Apixaban (25% ... if CrCl < 50) Edoxaban ... OralAnticoagulant #Anticoagulation ... #Pharmacology #Apixaban ... #Edoxaban #NOAC
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Clearance of Oral Anticoagulant ... Agents Warfarin ... Hepatic, 0% Renal Apixaban ... Hepatic, 80% Renal Edoxaban ... Hepatic, 50% Renal Rivaroxaban
Xa Inhibitors - Apixaban and Rivaroxaban Oral Xa inhibitors are recommended by CHEST as first-line for
patients with VTE ... Fibrillation requiring anticoagulation ... indications and edoxaban ... for VTE tx and ... #Rivaroxaban #Dosing
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
Currently, edoxaban ... and rivaroxaban ... for appropriate dosing ... body mass index; VTE ... Cancer #Algorithm #Anticoagulation
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 Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Pathophysiology Anticoagulation ... the mainstay of VTE ... (e.g. warfarin) ... for chronic anticoagulation ... DOAC #Dabigatran #Apixaban
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