1269 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Dabigatran #Apixaban #Rivaroxaban ... #Pharmacology #Hematology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
VKA, Dabigatran, Rivaroxaban ... anticoagulation #Switching #hematology
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
Anti-Coagulants • Rivaroxaban ... #Prescribing #hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Edoxaban (Lixiana), Rivaroxaban ... #pharmacology #hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
60kg, CrCl 15-50 Rivaroxaban ... Anticoagulation #Hematology ... Pharmacology #Apixaban #Rivaroxaban
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
Edoxaban, rivaroxaban ... Rivaroxaban and ... Chemotherapy #Oncology #Hematology
Quick Guide to Reversing Antiplatelet and Antithrombotic Therapy
Aspirin, Clopidogrel, Prasugrel, Ticagrelor, Abciximab, Tirofiban, Eptifibatide, Unfractionated Heparin,
Betrixaban, Edoxaban, Rivaroxaban ... anticoagulation #agents #hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
, edoxaban and rivaroxaban ... Anticoagulation #Management #Hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
Apixaban, Edoxaban or Rivaroxaban ... anticoagulant #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
diagnosis #models #hematology ... inhibitor #Apixaban #Rivaroxaban