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rheumatology management ana lupus systemic antibodies arthritis arthropathies arthropathy autoantibodies causes disease disorders gravis inflammatory joint jointpain laboratory monoarthritis monoarticular
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Diagnosis Algorithm ... Erythematosus ( ... SLE), should have ... Joint #Disorders #msk ... Diagnosis #Algorithm
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... 40% Target: SS-A/Ro ... is clinically suspected ... #erythematosus ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... Kumfer @AnnKumfer #Antinuclear ... #rheumatology #diagnosis ... #differential
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
Diagnosis Algorithm ... Arthritis • Systemic Lupus ... Erythematosus ... Inflammatory #JointPain #MSK ... Diagnosis #Algorithm
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus ( ... SLE) - Antinuclear ... (to support a diagnosis ... ANA and RF (if clinical
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Antibodies: Anti-Ro ... ab • RF • Antinuclear ... salivary ducts Clinical ... phenomenon (16%) MSK
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... life-threatening Differential ... myasthenia Diagnosis ... immunologic assay - MuSK ... #management #neurology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... Evaluate for NMO, SLE ... Disorders: - SLE ... #management #neurology ... #differential
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