17 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... and CNS • Headache
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus ( ... SLE) Clinical ... #Erythematosus ... #SLE #CNS #neurology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Can also be measured ... 40% Target: SS-A/Ro ... is clinically suspected ... #erythematosus ... #diagnosis #rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
nervous system (CNS ... syndrome • Systemic lupus ... erythematosus ... #Syndromes #neurology ... #inflammatory #differential
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
clinically significant ... erythematosus ( ... erythematosus ( ... #rheumatology #diagnosis ... #differential
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Compatible syndrome + MRI ... nodules, may also see ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Diagnosis Framework ... on clinical presentation ... Imaging: - MRI ... #Infections #differential
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
nervous system (CNS ... neuropathy (LHON) plus MRI ... lesions and clinical ... #Syndromes #neurology ... noninflammatory #differential
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... Disorders: - SLE ... #management #neurology ... #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
6th Decades (can be ... overlaps with RA, SLE ... Antibodies: Anti-Ro ... salivary ducts Clinical ... phenomenon (16%) MSK