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management neurology rheumatology anticoagulation aps cerebritis cns erythematosus gravis guidelines hematology hypercoagulable lupus myasthenia sjogrens sle systemic workup
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Syndrome (APS) ... ): • Lupus anticoagulant ... 1 of the three aPLs ... to be present Treatment ... #Syndrome #APS
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... (for secondary APS
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Syndrome (APLS) ... - 1 or more clinical ... maternal chromosomal causes ... excluded Testing: • Lupus ... #diagnosis #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... Generalized fatigue - ALS ... myasthenia Diagnosis ... immunologic assay - MuSK ... Myasthenia #Gravis #diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Antibodies: Anti-Ro ... Antibodies: • Anti-Ro ... salivary ducts Clinical ... phenomenon (16%) MSK ... Adenocarcinoma Treatment
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