9 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... , Acute hemolysis ... , deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
- Little or no nutritional ... -DPG -> - hemolysis ... - anemia ... #diagnosis #pathophysiology ... #symptoms #signs
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
initiation of nutrition ... overload) Other Symptoms ... • Seizures • Hemolysis ... hyperparathyroidism Treatment ... #Diagnosis #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... - ACS, AKI, acute ... : • Pathophysiology ... diagnosis #management #hematology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
breath, wasting, anemia ... Psychiatric symptoms ... Loss of teeth Anemia ... contribute to nonimmune hemolysis ... vasculitis Treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Platelet Disorders • Nutritional ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... workup #oncology #hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... clonal evolution to acute ... disease tolerate anemia ... #algorithm #hematology