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rheumatology diagnosis differential management acr2021 treatment guidelines classification dermatology gca giantcell granulomatosis polyangiitis gpa nephrology syndrome tak aortitis causes cryofibrinogenemia
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Vasculitis 1 ... 3 types 2) Vasculitis ... • Arthralgia, arthritis ... #Vasculitis #Diagnosis ... #Rheumatology #
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Urticarial/LCV) - Cryoglobulinemic ... ANCA Associated: ... : • Temporal arteritis ... • Takayasu's arteritis ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and often causes arthritis ... +MPO) • Cryoglobulinemic ... Vasculitis: + MPO-ANCA ... Low levels mixed cryoglobulinemia ... differential #diagnosis #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
vasculitis (Eosinophilic ... vasculitis, Behcet ... disease, Cryoglobulinemia ... erythematosus, Rheumatoid arthritis ... → confirm DAH, rule
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Lupus Nephritis, Cryoglobulinemia ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthralgia, and arthritis ... DDX: • ANCA (Antineutrophil ... SLE), rheumatoid arthritis ... classification #rheumatology ... #vasculitis
2021 ACR/VF Guidelines for Management of Giant Cell Arteritis (GCA) #GiantCell #Arteritis #GCA #ACR2021 #Management #rheumatology #algorithm
of Giant Cell Arteritis ... ) #GiantCell #Arteritis ... ACR2021 #Management #rheumatology ... #algorithm #vasculitis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... : Giant Cell Arteritis ... Nodosa (PAN), ANCA ... associated vasculitis ... Differential #Diagnosis #rheumatology
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
affects large arteries ... affects medium arteries ... rarely affects arteries ... basement membrane; ANCA ... #Diagnosis #Rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
large vessels - Arteritis ... temporalis (giant-cell arteritis ... - Takayasu arteritis ... small vessels - ANCA-associated ... Vessels #Diagnosis #Rheumatology
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