31 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... • Increased Serum ... Hemolysis #Hemolytic #Anemia ... #Workup #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Serum B12 - Anti-IF ... - Low Serum B12 ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... with Low Mean Corpuscular ... - Differential Diagnosis ... #Differential #Diagnosis ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... Algorithm Low ... #Algorithm #Causes ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... MCV, MCH, MCHC, Serum ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Diagnostic Framework ... for Anemia (Morphological ... Approach - MCV) Low ... #differential #diagnosis ... #causes #hematology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Differential Diagnosis ... fast - Too slow ... Transverse myelitis • Hematology ... : - Anemia • ... #differential #diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
If the value is low ... result in severe anemia ... immune hemolytic anemia ... Mild-to-moderate elevation Serum ... #Workup #Hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... : • Low serum IgG ... 300 mg/dL) • Low ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes ... • Elevation of serum