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hematology management blood reactions adjusted age classification coagulation comatose dic differential dimer disseminated fungal hodgkins infections infectiousdiseases intravascular leukostasis lymphoma
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
D-dimer is a product ... age, which can cause ... specificity is 0-18% How ... #dimer #pathophysiology ... #diagnosis #age
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
If the value is low ... Fibrin degradation products ... or D-dimer - Normal ... Mild-to-moderate elevation Serum ... #Workup #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Prolonged PT/PTT • Low ... protein C and S Pathophysiology ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... RBCs binds to serum ... Hypothermia: Due to low ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... RBCs binds to serum ... Hypothermia: Due to low ... #Transfusion #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
genes and gene products ... Blood Count - Low ... may be high or low ... • Increased Serum ... • Increased Serum
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Mutism Pathophysiology ... Casey Albin MD @ ... caseyalbin #PhysicalExam ... #diagnosis
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... dissemination occurs and produces ... protein level • A low ... prep CSF and serum ... Aspergillosis Pathophysiology
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