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hematology treatment nephrotic sle testing blood classification comparison differential disease druginduced erythematosus glomerular hyponatremia nephritic product reactions sodium syndrome systemic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... 60-80% - Low ... #rheumatology
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome == Nephrotic Syndrome == Onset - Insidious Edema - ++++ Blood
pressure - Normal/low ... - Absent Serum ... albumin - Low ... Nephritic #Comparison #Table ... #Nephrology #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... in >90% - Low ... sle #comparison #table ... #rheumatology # ... diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... permeability Diagnosis ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
: • Low serum IgG ... 300 mg/dL) • Low ... and M panel Management ... DDX - Other causes ... #diagnosis #management
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
protease activity - A low ... activity is the diagnostic ... If the value is low ... Mild-to-moderate elevation Serum ... #Workup #Hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... factor level • Low ... (e.g. systemic lupus ... classification #rheumatology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... algorithm Urine Na+K / serum ... #differential #diagnosis ... #table #sodium ... #nephrology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... chest wall, and low ... #diagnosis #testing ... #Rheumatology
Hyponatremia - Diagnosis and Treatment Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... 3 questions to work ... Calculate serum ... #Treatment #management ... #nephrology #sodium
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