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differential neurology blood infections infectiousdiseases product reactions syndrome alkaline alp associated autoimmune causes coagulation dementia dic disorder disseminated fungal hand
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Diagnosis Framework ... sensitivity of serum ... #AIDS #opportunistic ... InfectiousDiseases #Neurology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
membrane into the CNS ... collection with EDTA Pathophysiology ... mineralization Symptoms ... • Elevation of serum ... Hyophosphatasia #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Prolonged PT/PTT • Low ... protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... #Coagulation #diagnosis ... #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
/AIDS patients ... be present: • AIDS ... with low pretreatment ... pleural effusions, CNS ... #Management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
RBCs binds to serum ... Hypothermia: Due to low ... Extremely rare - HIV ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
RBCs binds to serum ... Hypothermia: Due to low ... Extremely rare - HIV ... #Transfusions #diagnosis ... #management #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... that results in CNS ... Bilateral signs and/or symptoms ... simplex virus, HIV ... #management #neurology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
yeast • At risk: AIDS ... protein level • A low ... prep CSF and serum ... Aspergillosis Pathophysiology ... #Management #Infections
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