18 results
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
- Serum to Ascites ... • Produced by a ... oncotic pressure Low ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Diagnosis Framework ... sensitivity of serum ... #AIDS #opportunistic ... InfectiousDiseases #Neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
membrane into the CNS ... deficiency • blood ... collection with EDTA Pathophysiology ... mineralization Symptoms ... • Elevation of serum
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
of high parity blood ... : 2 hit mechanism ... to explain symptoms ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... RBCs binds to serum ... Blood products contain ... Hypothermia: Due to low ... #diagnosis #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
RBCs binds to serum ... Blood products contain ... Hypothermia: Due to low ... #diagnosis #management ... #hematology #reactions
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of fibrin split products ... which can plug blood ... precipitate in serum ... Cryofibrinogenemia Symptoms ... hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
originate from a low-grade ... Agglutinin Syndrome (CAS ... Mycoplasma, EBV, HIV ... sensitize red blood ... hemolytic #anemia #hematology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Specificity: - Serum ... infection (IFI) in hematologic ... products - ... products - ... Galactomannan #diagnosis