13 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... sensitivity of serum ... #AIDS #opportunistic ... #InfectiousDiseases ... #Neurology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... to explain symptoms ... Transfusion #Reactions #hematology ... #diagnosis #comparison
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis ... #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
collection with EDTA Pathophysiology ... mineralization Symptoms ... • Elevation of serum ... Hyophosphatasia #hepatology ... #diagnosis
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
- Differential Diagnosis ... (It's usually low ... Constitutional symptoms ... #AIDS #pulmonary ... #infectiousdiseases
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
yeast • At risk: AIDS ... protein level • A low ... prep CSF and serum ... Aspergillosis Pathophysiology ... ) #Mycoses #InfectiousDiseases
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Slow Growers (Runyon ... Hematologic malignancy ... gastrointestinal symptoms ... • Clinical (Symptoms ... #infectiousdiseases
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
RBCs binds to serum ... Hypothermia: Due to low ... Extremely rare - HIV ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
RBCs binds to serum ... Hypothermia: Due to low ... Extremely rare - HIV ... #Transfusions #diagnosis ... #management #hematology