15 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... blood donor • Pathophysiology ... : 2 hit mechanism ... to explain symptoms ... #hematology #diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
TRALI resembles ARDS ... RBCs binds to serum ... Hypothermia: Due to low ... #Transfusion #diagnosis ... #management #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
/ AIDS - Differential ... Diagnosis Framework ... sensitivity of serum ... #AIDS #opportunistic ... InfectiousDiseases #Neurology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... Diagnosis: MRI ... disorder #dementia #AIDS ... #Neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... contents into serum ... , Elevated Cr, Low ... Syndrome #TLS #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
TRALI resembles ARDS ... RBCs binds to serum ... Hypothermia: Due to low ... #Transfusions #diagnosis ... #management #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
collection with EDTA Pathophysiology ... mineralization Symptoms ... • Elevation of serum ... Hyophosphatasia #hepatology ... #diagnosis
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary
Use a positive diagnostic strategy with minimal testing.
Rome IV Criteria ... last 3 months + symptom ... /o red flags - Low ... unless reproducible reactions ... Gastroenterology and Hepatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
/AIDS patients ... be present: • AIDS ... with low pretreatment ... superinfection, drug reactions ... : • Drug reaction
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
A reaction to phagocytosed ... • NSAIDs • Low-dose ... • Concomitant low-dose ... allopurinol • IV ... severe allergic reactions