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hematology neurology symptoms als amyotrophic anorexianervosa antinxp2 antinxp2dm bullous complications differential dm hemeonc hemophagocytic hlh lateral leukostasis lymphohistiocytosis lysis myelitis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... enzyme levels in serum ... Polymyositis #PM #Diagnosis ... #Pathophysiology ... #Signs #Symptoms
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... dermis Clinical Signs ... Bullous #Pemphigoid #Diagnosis ... #Management #dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... contents into serum ... Syndrome #TLS #diagnosis ... #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... Abnormally low serum ... present, symptoms, signs ... #Management #Summary ... #treatment #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology ... #diagnosis #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... levels of: • Serum ... : • ILD was diagnosed ... #diagnosis #management ... #rheumatology #dermatology
Scleroderma Renal Crisis - Diagnosis and management Diaqnosis • De novo arterial hypertension of normotensive form +++
and management ... Diaqnosis • ... • Increased serum ... creatinine >50% • Signs ... #management #nephrology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... • Bilateral signs ... Transverse Myelitis Diagnosis ... #management #neurology
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
- Females: Low Serum ... - Males: Low Serum ... risk of fracture DERMATOLOGIC ... Complications #pathophysiology ... #diagnosis #signs
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Presentation • Common Signs ... Pathophysiology ... Approach • Initial management ... #Management #Hematology
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