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Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
- Insidious Edema ... - Absent Serum ... Onset - Abrupt Edema ... - Present Serum ... Nephritic #Comparison #Table
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Hypokalemia, Erectile ... , Serum creatinine ... Angioneurotic edema ... , Hyperkalemia, ... contraindications #table
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
obtain the desired serum ... Side Effects: Edema ... constipation, diarrhea, nausea ... ); nausea, vomiting ... #pharmacology #table
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Hyporeflexia: • Hypercalcemia ... Deep coma (any cause ... differential #diagnosis #table ... #neurology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... transfusion • HTN and edema ... differential #diagnosis #causes ... potassium #high #nephrology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
retinal veins, serum ... Syndrome: • Facial edema ... Hyperphosphatemia • Hyperkalemia ... Hypocalcemia Hypercalcemia ... Constipation • Nausea
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... transfusion • HTN and edema ... differential #diagnosis #causes ... potassium #high #nephrology
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
since they are not able ... dose is based on serum ... restricted due to hypercalcemia ... Only* #CKD #Nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... only if no clear cause ... Elimination (see Table ... caution in HTN & edema ... Treatment #potassium #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... algorithm Urine Na+K / serum ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table ... #sodium #nephrology