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diagnosis differential management pharmacology potassium renal binders binding comparison crrt diuresis diuretics encephalopathy excretion hypokalemia hyponatremia hypotonic k managment modalities
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding Agents ... obtain the desired serum ... Side Effects: Edema ... #medications #pharmacology ... #table #comparison
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Diuretics and Agents ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... #Pharmacology #Medications ... #Table
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... only if no clear cause ... Elimination (see Table ... caution in HTN & edema ... Treatment #potassium #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Immunosuppressive agents ... Blood transfusion, Hypercalcemia ... Electrolyte abnormality, Medication ... the underlying cause ... with AEDs until cause
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table ... #sodium #nephrology
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... after correcting serum ... Other medications ... continued in most cases ... #nephrology
Renal Replacement Therapy (RRT) - ICU One Pager Summary Indications (AIEOU): • A: Acidosis (usually severe metabolic)
derangements (hyperkalemia ... , hypercalcemia, ... Overload (pulmonary edema ... chosen to match serum ... RRT #managment #nephrology
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