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hematology blood product reactions syndrome antinxp2 apml crisis dermatology dermatomyositis differentiation disease diuresis diuretics encephalopathy erythematosus excretion igg4 lupus medications
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
pancreas, biliary, renal ... lymph node), high serum ... hypergammaglobulinemia, ↑ acute ... #management #phenotypes ... workup #treatment #rheumatology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... irrigation • Management ... Torsemide) • Acute ... hyperaldosteronism • Acute ... Excretion #Diuresis #Nephrology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
myalgias, HoTN, edema ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... Renal Failure ... #management #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
matter vasogenic edema ... Immunosuppressive agents, Renal ... Neurological symptoms: Acute ... syndrome, ADEM, Acute ... #management #neurology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
levels of: • Serum ... • Clear cell renal ... three days #AntiNXP2DM ... #diagnosis #management ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Differential Diagnosis ... , and elevated serum ... APLA/LAC: • Renal ... #Rheumatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis: 1) Acute ... of arteries Management ... #Crisis #rheumatology ... #nephrology #diagnosis ... #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... , DIC, hypoTN, renal ... RBCs binds to serum ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... , DIC, hypoTN, renal ... RBCs binds to serum ... #Transfusions #diagnosis ... #management #hematology
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