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SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... SAPHO syndrome is ... Pustular skin lesions ... oral retinoid • SAPHO ... #SAPHO #Syndrome
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
Pustular Skin Lesions ... SAPHO syndrome ( ... Pustular #Skin #Lesions
Skin Lesion Guide - Atlas
#Diagnosis #Dermatology #Skin #Lesions #Terminology #Nomenclature #Atlas #Key #Basics
Skin Lesion Guide ... Dermatology #Skin #Lesions
Dermatology Skin Lesion Atlas

#Skin #Lesions #Atlas #Map #Nomenclature #Dermatology #Naming #Terminology #Clinical

** GrepMed Recommended Text: Fitzpatrick's
Dermatology Skin Lesion ... Atlas #Skin #Lesions
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Ring-Enhancing Lesions ... Ring-Enhancing Lesions ... syndrome + MRI lesions ... present w/ CNS lesions ... also see skin lesions
Illustrative examples of culture-confirmed erythema migrans. A, A single erythema migrans lesion of 8.5 × 5.0
erythema migrans lesion ... The lesion is homogeneous ... erythema migrans lesions ... clearing of the lesions
CNS Ring-Enhancing Lesions - Differential Diagnosis
 • Infections: Cerebral abscess (bacterial, fungal, parasitic), Neurocysticercosis, Tuberculoma, Cerebral
Ring-Enhancing Lesions ... usually multiple lesions ... usually solitary lesion ... Ring #Enhancing #Lesions
Morphology of Skin Lesions - Primary and Secondary - Description Algorithm
 • Primary Skin Lesion -
Morphology of Skin Lesions ... • Primary Skin Lesion ... - Initial lesion ... Secondary Skin Lesion ... - Lesion that develops
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Auto-Inflammatory: PAPA, SAPHO ... Auto-Inflammatory: SAPHO
Janeway Lesion: Flat, painless, erythematous lesions seen on the palm of this patient's hand. While
frequently associated
Janeway Lesion: ... , erythematous lesions ... SkinRash #Janeway #Lesions