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vasculitis myopathy myositis pain antimda5 antimda5dm antinxp2dm autoimmune classification conditions cutaneous defects dermatologic erythematosus extrarticular gap globulin granulomatosis inherited lupus
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Sarcoidosis • GPA ... Sarcoidosis #dermatology ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
surfaces of the joints ... reticularis Differential ... Diagnosis: Vasculitis ... #dermatology #rash ... #diagnosis #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
- Differential ... Diagnosis Framework ... - GPA Cutaneous ... #dermatology #rheumatology ... diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... vasculitis - GPA ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... myopathy) VA Joint ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
interphalangeal joints ... ulcerations • Skin ... 50% of cases • Skin ... #rheumatology # ... dermatology #diagnosis
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
interphalangeal joints ... : • ILD was diagnosed ... #AntiNXP2 #Dermatomyositis ... #rheumatology # ... dermatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Scleroderma Thickened skin ... Heberden's nodes (DIP joints ... #pain #differential ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis Framework ... > PR3 60% • GPA ... vesicular eruption - Joints ... • ANCA (Dx: GPA ... #diagnosis #rheumatology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
due to a lack of GP ... due to a lack of GP ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
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