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erythematosus leukemia lupus systemic workup chronic classification clinical cll cutaneous hemolytic lymphocytic manifestations mds monoclonal myelodysplasia nonpalpable pain palpable paraproteinemias
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... dermatomyositis, SLE ... #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Sarcoidosis #dermatology ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Hemolytic anemia ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... #diagnosis #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... ): SS, SC, SE, Sβ ... cardiac valve, vasculitis ... Diagnosis #Algorithm ... #workup #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... Presentation - Systemic Symptoms ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... just beneath the skin ... Myeloproliferative Disease ... #Syndromes #diagnosis ... #hematology #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... , such as SLE, atherosclerotic ... #Differential #Diagnosis ... #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS+GI+CVS+joints ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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