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erythematosus leukemia lupus oncology pain vasculitis arthritis autoimmune behcet classification conditions disease extrarticular lymphocytic management monoarthritis msk myopathy myositis oligoarthritis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Sjögrens (15%) Skin ... Demyelinating syndromes ... #signs #symptoms ... #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... ) CLL Symptoms: ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin ... workup #oncology #hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Genitourinary system ... Scleroderma Thickened skin ... #pain #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Diagnosis Framework ... noninflammatory Signs ... constitutional symptoms ... #rheumatology # ... Monoarticular #Monoarthritis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Behcet disease) Differential ... Recurrent and chronic ... #signs #symptoms ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... diseases, such as SLE ... purpura: Strong sign ... Eosinophilia, asthma, chronic ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis: Systemic ... Symptoms (Sx) in ... purpura: strong sign ... vasculitis, and SLE ... #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
) • Anti-Mi2 (skin ... ) • Shawl sign ... : Fever, joint pain ... • Conduction system ... Myositis #Myopathy #rheumatology
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