13 results
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Henoch Schonlein ... suggestive of Henoch-Schonlein ... purpura (IgA), ... #Schonlein #Purpura ... #photo #dermatology
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
(HSP, IgA Vasculitis ... #Henoch #Schonlein ... #HSP #IgA #Vasculitis ... #clinical #photo ... #dermatology #skin
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
the Skin - Differential ... Petechiae, Palpable purpura ... Urticarial/LCV) - Cryoglobulinemic ... #Vasculitis #skin ... #dermatology #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Skin ulcers ... Syndrome: • Clinical ... • IgA vasculitis ... (Henoch-Schönlein ... purpura) • Cutaneous
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
correlations • Purpura ... Identification of causes ... : SLE +++ • IgA ... #dermatology #semiology ... signs #lesions #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... Normal Complement: IgA ... nephropathy, Henoch-SchonIein ... Purpura Anti-GBM ... #differential #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Diagnosis: Vasculitis ... polyangiitis • EGPA • Henoch-Schönlein ... cryoglobulinemia
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Henoch Scholein ... Purpura: Pathogenesis ... and Clinical Findings ... response) - Cutaneous
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... • Ig A vasculitis ... /HSP • Cryoglobulinemia ... Diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Schonlein Purpura ... (IgA vasculitis ... tract, and often causes ... Vasculitis - Skin ... differential #diagnosis