78 results
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
Clinical Trials of SGLT2 ... ASCVD; signal for SGLT2i ... risk; signal for SGLT2i ... HF outcomes in HFrEF ... HF outcomes in HFrEF
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
@DharSaty #HFrEF ... sodium-glucosecotransporter-2inhibitors #SGLT2i
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
Therapy (GDMT) in HFrEF ... Class I pillars of HFrEF ... diuretics, MRA, SGLT2i ... therapies" for HFrEF ... commonly used in HFrEF
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
Ejection Fraction (HFrEF ... Beta-Blocker → MRA → SGLT ... Beta-Blocker + SGLT ... #Failure #CHF #HFrEF
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
Ejection Fraction (HFrEF ... ARNI • MRA • SGLT ... #Failure #CHF #HFrEF
SGLT2 Inhibitors and Cardiovascular Pathophysiology

#SGLT2i #Inhibitors #Cardiovascular #Pathophysiology
SGLT2 Inhibitors ... Pathophysiology #SGLT2i
Congestive Heart Failure - Causes, Pathophysiology and Differential Diagnosis
 • Dilated Cardiomyopathy 
 • Hypertrophic Cardiomyopathy
Cardiomyopathy HFrEF ... Infectious • Other HFpEF ... Diagnosis #cardiology #HFrEF ... #HFpEF #CHF
Cardiovascular and renal effects comparison between SGLT-2 inhibitors
 - Canagliflozin (Invokana)
 - Dapagliflozin (Farxiga)
 - Empagliflozin
comparison between SGLT ... cardiovascular #renal #SGLT2i
Oral Antihypertensive Medications - Selection by Comorbidities
Comorbidities: 
 • Stable Angina, HFpEF, HFrEF, AFib, TAA/Marfan, Aortic
Stable Angina, HFpEF ... , HFrEF, AFib, TAA
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
SGLT2 Inhibitors ... in those on an SGLT2i ... is closed • SGLT2 ... Kat_Watson #SGLT2