SJS clinical msk - GrepMed

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Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

SJS-TEN overlap and TEN - Surface Epidermal

Stevens-Johnson syndrome (SJS ... and Overlap SJS-TEN ... Distinguishing Features #SJS

Tweetorial - Stevens Johnson Syndrome (SJS)

By Dr. Steven Chen @DrStevenTChen

#StevensJohnsonSyndrome #SJS #Dermatology #Diagnosis #Tweetorial #Pathphysiology

Johnson Syndrome (SJS ... StevensJohnsonSyndrome #SJS

Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
• Homogeneous pattern:
-

pattern: - SjS ... Raynaud phenomenon, SjS ... PBC/SSc OS, PBC/SjS ... Speckled: - SLE, SjS ... polar: - SLE, SjS

DRESS Syndrome vs SJS/TEN
DRESS
• Latency: 2-8 weeks
• Rash: Morbilliform
• Mucosal involvement: 50% have

DRESS Syndrome vs SJS ... lymphocytes and eos SJS ... DRESS #Syndrome #SJS

Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS
- Onset:

Comparison - DRESS | SJS ... target lesions SJS

Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM

to Weeks (Rash, SJS

ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,

(Strep/Staph), SJS ... or Pustular: SJS

Fever and Rash - Differential Diagnosis Framework
• Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,

Noninfectious: SJS

Clarke's Test (Patellar Grind Test)

Indicates Patellofemoral dysfunction.
- Patient with knee in extension. Push posterior on

of patella then ask ... Patellar #Grind #clinical ... Patellofemoral #msk

$5th metatarsal distal shaft fracture - Fracture detection on MSK ultrasound The Ultrasound Site - MSK ultrasound$

Fracture detection on MSK ... Ultrasound Site - MSK ... shaft #fracture #MSK ... POCUS #Ultrasound #Clinical

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