17 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
and Cytoplasmic Patterns ... Nuclear Patterns ... • Homogeneous pattern ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Patterns Homogeneous ... pattern: • SLE ... ) Nuclear dots pattern ... #Patterns #differential ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... diagnosis #differential
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... scleroderma (SSc) • Nucleolar ... Antibodies #ANA #patterns ... #rheumatology # ... diagnosis #differential
Pulmonary complications of targeted therapy
-Immune checkpoint inhibitors (e.g. pembrolizumab)
-Pneumonitis is uncommon (~5% of patients) but can
checkpoint inhibitors (e.g ... , and the most common ... There are case reports ... pneumonitis, but it’s unclear ... PulmonaryComplications #Patterns
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... gastric bypass), LFT ... #Diagnosis #Causes ... #Workup #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
disease or more commonly ... GPA causes disease ... reticularis Differential ... with a certain pattern ... #diagnosis #rheumatology
Pulmonary Embolism on ECG 

Mid 30's female with chest pain/dyspnea.  Triage EKG (no prior).
Triage EKG (no prior ... Differential/diagnosis ... See thread for POCUS ... (II, III, AVF)(pattern ... seen in 34% of cases
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
being the most common ... Imaging Patterns ... Reversible course Differential ... the underlying cause ... with AEDs until cause
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... mucositis - Rash ... - (C-ANCA) pattern ... - (P-ANCA) pattern ... #diagnosis #rheumatology