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Thrombotic Microangiopathies In Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Systemic Lupus Erythematosus ... Systemic #Lupus #Erythematosus ... #SLE #hematology ... #rheumatology # ... differential #diagnosis
An Approach to the Unknown Rash: Erythematous Rash 

#Diagnosis #Dermatology #Erythematous #Rash #Differential #Algorithm #Nikolsky #Sign
to the Unknown Rash ... : Erythematous Rash ... #Dermatology #Erythematous ... #Rash #Differential
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... Vesicopustule on erythematous ... #skin #rashes #differential ... #diagnosis #rheumatology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs SJS ... : 2-8 weeks • Rash ... lymphocytes and eos SJS ... : 4-28 days • Rash ... : Painful erythematous
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
skin syndrome (SSS ... Nikolsky sign, the differential ... rash but without ... #Rash #Algorithm ... Febrile #Fever #Differential
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Systemic lupus erythematosus ... Systemic lupus erythematosus ... Sjogren's Syndrome (SS ... ANA #patterns #rheumatology ... #diagnosis #differential
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Anti-phospholipid) M Malar Rash ... D Discoid Rash ... systemic #lupus #erythematosus ... #rheumatology #
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Differential Diagnosis ... Noninfectious: SJS ... SCVMCMed #Fever #Rash ... #Differential #
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Pediatrics Patient - Differential ... butterfly-like erythematous ... lighter center and erythematous ... hyperpigmented or erythematous ... arthritis #skin #differential
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
Comparison - DRESS | SJS ... target lesions SJS ... - Features: Erythematous ... Dermatology #Emergency #Differential