1555 results
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... drug reaction • SJS ... disease: symptomatic treatment
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs SJS ... : 2-8 weeks • Rash ... lymphocytes and eos SJS ... : 4-28 days • Rash ... DRESS #Syndrome #SJS
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Noninfectious: SJS ... SCVMCMed #Fever #Rash
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
Days to Weeks (Rash ... , SJS) - Amelia
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
Approach to Fever and Rash ... (Strep/Staph), SJS ... or Pustular: SJS ... WuidQ #Fever #Rash
Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

 SJS-TEN overlap and TEN - Surface Epidermal
Stevens-Johnson syndrome (SJS ... and Overlap SJS-TEN ... Distinguishing Features #SJS
Tweetorial - Stevens Johnson Syndrome (SJS)

By Dr. Steven Chen @DrStevenTChen

#StevensJohnsonSyndrome #SJS #Dermatology #Diagnosis #Tweetorial #Pathphysiology
Johnson Syndrome (SJS ... StevensJohnsonSyndrome #SJS
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
distribution of the rash ... and whether the rash ... pathognomonic for SJS ... peripherally distributed rash ... Maculopapular #Rash
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SjS ... Raynaud phenomenon, SjS ... PBC/SSc OS, PBC/SjS ... Speckled: - SLE, SjS ... polar: - SLE, SjS
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... Skin rash and malaise ... with or without treatment ... , but without treatment ... ▪ “Rash” (75%