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Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

 SJS-TEN overlap and TEN - Surface Epidermal
Stevens-Johnson syndrome ... (SJS), Toxic epidermal ... and Overlap SJS-TEN ... Distinguishing Features #SJS ... Stevens #Johnsons #Syndrome
Tweetorial - Stevens Johnson Syndrome (SJS)

By Dr. Steven Chen @DrStevenTChen

#StevensJohnsonSyndrome #SJS #Dermatology #Diagnosis #Tweetorial #Pathphysiology
Stevens Johnson Syndrome ... (SJS) By Dr. ... StevensJohnsonSyndrome #SJS
Stevens-Johnson Syndrome (SJS) - Appeared 4 days after starting antibiotic therapy

#Stevens #Johnson #Syndrome #SJS #clinical #video
Stevens-Johnson Syndrome ... (SJS) - Appeared ... Stevens #Johnson #Syndrome ... #SJS #clinical
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... SJS/TEN DRESS ... lymphocytes and eos SJS ... SCVMCMed #DRESS #Syndrome ... #SJS #TEN #comparison
Causes of Pharyngitis - Differential Diagnosis
Infectious:
 • Bacterial: Group A Strep, Group B and C Strep,
Lupus, Behcet syndrome ... Autoinflammatory syndromes ... stomatitis Drugs: SJS
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
diseases, Toxic shock syndrome ... Noninfectious: SJS ... , DRESS, Sweet syndrome
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
(Strep/Staph), SJS ... or Pustular: SJS ... angiomatosis, Sweet syndrome
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... Staphylococcal scalded skin syndrome ... Video #Clinical #SJS
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
NMS, serotonin syndrome ... effect/reaction (ie SJS
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
drug reaction • SJS ... SinaiBmoreIMRes #DRESS #Syndrome