1292 results
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Immunocompromise Treatment ... • Secondary to Treatment ... effect/reaction (ie SJS
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
drug reaction • SJS ... disease: symptomatic treatment
Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

 SJS-TEN overlap and TEN - Surface Epidermal
Stevens-Johnson syndrome (SJS ... and Overlap SJS-TEN ... Distinguishing Features #SJS
Tweetorial - Stevens Johnson Syndrome (SJS)

By Dr. Steven Chen @DrStevenTChen

#StevensJohnsonSyndrome #SJS #Dermatology #Diagnosis #Tweetorial #Pathphysiology
Johnson Syndrome (SJS ... StevensJohnsonSyndrome #SJS
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
pattern: - SjS ... Raynaud phenomenon, SjS ... PBC/SSc OS, PBC/SjS ... Speckled: - SLE, SjS ... polar: - SLE, SjS
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs SJS ... lymphocytes and eos SJS ... DRESS #Syndrome #SJS
Antibiotics for Intraabdominal Infection. 
Use your local antimicrobial susceptibility data for selecting the best empiric treatment!
the best empiric treatment ... the WSES/GAIS/SIS-E ... #pharmacology #treatment
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
Comparison - DRESS | SJS ... target lesions SJS
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
to Weeks (Rash, SJS
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
(Strep/Staph), SJS ... or Pustular: SJS