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Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD EMPA-REG OUTCOME - Empagliflozin lowered CV events
Clinical Trials of SGLT2 ... ASCVD; signal for SGLT2i ... risk; signal for SGLT2i ... outcomes trial in SGLT2i ... mcclaffertyMD #SGLT2
How SGLT2 inhibitors block glucose reabsorption in proximal tubule and improve systemic glucose homeostasis: https://www.ajkd.org/article/S0272-6386(18)30633-4/fulltext #Pathophysiology #Mechanism #Nephrology
How SGLT2 inhibitors ... Mechanism #Nephrology #SLGT2
SGLT2 Inhibitors and Cardiovascular Pathophysiology #SGLT2i #Inhibitors #Cardiovascular #Pathophysiology
SGLT2 Inhibitors ... Pathophysiology #SGLT2i
Pathophysiology Euglycemic DKA - Mechanism of SGLT-2 Inhibitors #Pathophys #Endocrine #Euglycemic #DKA #SGLT2 #Mechanism
- Mechanism of SGLT ... Euglycemic #DKA #SGLT2
SGLT2 Inhibitors and Euglycemic DKA Risk factors for euglycemic DKA in those on an SGLT2i include: •
SGLT2 Inhibitors ... in those on an SGLT2i ... is closed • SGLT2 ... Kat_Watson #SGLT2
Indications for and pharmacological properties of approved SGLT2 inhibitors Canagliflozin - Dapagliflozin - Empagliflozin - Ertugliflozin #SGLT2 #Inhibitors
properties of approved SGLT2 ... Ertugliflozin #SGLT2
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
-4 inhibitors SGLT2 ... Improved outcomes in CKD
Stepwise Approach to Prescription of SGLT2 inhibitors Anticipatory Guidance • Consider diuretic dose reduction Patient Counseling
Prescription of SGLT2 ... endocrinologists #SGLT2
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
Metformin + SGLT2 ... dapagliflozin) Dpp4 + SGLT2
Metabolic Acidosis with Anion Gap - KILU Mnemonic K - Ketoacidosis • DKA - With normal glucose, ask if
glucose, ask if on SGLT2 ... ketoacidosis in SGLT2 ... inhibitors and SGLT2
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