17 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
lymphoproliferative disorders ... Hemoglobinopathies (e.g. sickle cell ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Hemolysis - Differential ... • Sickle cell ... Differential #Diagnosis ... Algorithm #Causes #Hematology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Increased red cell ... Increased red cell ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Ascites - Differential Diagnosis and Workup Algorithm

•
Perform paracentesis:
 • Cell count and diff 
 • Total
Ascites - Differential ... Diagnosis and Workup ... paracentesis: • Cell ... #Differential # ... gastroenterology #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Consider sickle cell ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... , Disseminated intravascular ... key #diagnosis #differential ... #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... younger pts) Differential ... sensitize red blood cells ... the RBCs causing intravascular ... #anemia #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Splenomegaly - Differential ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... Disease • Sickle Cell ... Algorithm #Causes #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... /µL Workup • Screen ... #Algorithm #Differential ... #diagnosis #hematology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
Approach and Differential ... Routine tests: Cell ... count and differential ... #workup #Differential ... #Diagnosis #hepatology