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diagnosis differential psychiatry pharmacology algorithm pathophysiology signs symptoms antidepressants comparison data ebm evidence hyponatremia inhibitors management negativetrials nejm policy publication
Selective Publication of Antidepressant Trials A more complete picture: contrasting the journal version of antidepressant trials with
trials with the FDA ... Antidepressants #SSRIs ... #Publication #Bias ... #Comparison #FDA
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 Neuromodulators for Disorders of Gut Brain Interactions (DGBIs) SSRIs - When anxiety, depression, and phobic features are
Interactions (DGBIs) SSRIs ... early satiety nausea ... disturbed sleep SNRls ... Ligand Agents • SSRI
Selective Publication of Antidepressant Trials A more complete picture: contrasting the journal version of antidepressant trials with
trials with the FDA ... Antidepressants #SSRIs ... #Publication #Bias ... #Comparison #FDA
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Akathisia • SSRI ... Dizziness - Nausea ... sensations) #SSRIs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Reuptake Inhibitors(SNRIs ... Diarrhea, Insomnia, Nausea ... gain Incr NE: Nausea ... Dry Mouth #SNRIs
Causes of Hyperpyrexia (Temp > 106.7° F) - Differential Diagnosis • Heat Stroke • Drug-induced: Amphetamines,
Causes of Hyperpyrexia ... Serotonin syndrome: SSRIs ... Differential #Diagnosis #Causes
Secondary causes of Hypertension • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Secondary causes ... Pseudopheochromocytoma - respond to SSRIs ... Other Endocrine causes ... low renin HTN causes ... #Secondary #causes
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
treat underlying cause ... Stress, Nausea, ... Meds (Opiates, SSRIs
Causes of Depressed / Lethargic Newborn - Differential Diagnosis Algorithm Maternal Related: • Drugs (Ex. SSRI) •
Causes of Depressed ... SSRI) • Diabetes ... Sepsis Other: • Anemia ... Diagnosis #Algorithm #Causes
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
cyclosporine, SSRIs ... Diagnosis #Table #Causes
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