38 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... hyperglycemia in type 2 diabetes ... commonly used diabetes ... /ambcarerx #Diabetes ... #Drug #Endocrinology
Summary table of mechanism of action, side effect and contraindications of commonly used diabetic drugs. 

#pharmacology
commonly used diabetic ... drugs. ... pharmacology #dm2 #diabetes ... #medications #overview
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
Diabetesdiabetic ... applied to the diabetic ... primary cause of diabetic ... - Cytokines #Pathophysiology ... #Nephrology #CKD
SNRls (Serotonin/Norepinephrine Reuptake Inhibitors) - FDA Approved Indications 

Venlafaxine (Effexor) - GAD, MDD, Panic Disorder, SAD
SNRls (Serotonin ... Cymbalta) - GAD, MDD, Diabetic ... There are 5 SNRI's ... purpose of these medications ... /ambcarerx #SNRls
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... Medications ... sarahthelyon #Diabetes ... #Medications #pharmacology ... #pathophysiology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... medications, with ... Benefits of these drugs ... #Pharmacology #Medications ... #DM2 #Diabetes
Drugs causing hyperkalemia
 • Impaired release of renin: NSAIDs, Beta blockers, Cyclosporine, tacrolimus, Diabetes, Elderly
 •
Drugs causing hyperkalemia ... Cyclosporine, tacrolimus, Diabetes ... Drospirenone #Drugs ... #hyperkalemia #medications
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Inhibitors Increasing Indications ... Significant Adverse Drug ... level < 200 mg/dL Pathophysiology ... #Euglycemic #Diabetic
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
renal failure • Drugs ... uropathies • Drugs ... • Diabetic Nephropathy ... hyperplasia • Drugs ... Diagnosis #algorithm #nephrology
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Classification of Diabetes ... or neurogenic diabetes ... Idiopathic Nephrogenic diabetes ... or dipsogenic diabetes ... #Diabetes #Insipidus