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Hypomagnesemia - Differential Diagnosis
Renal Causes of Hypomagnesemia - Familial:
Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Differential Diagnosis ... and Gitelman syndrome ... - Acquired: Medications ... #differential # ... diagnosis #causes #nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Hypomagnesemia - ... diarrhea / IBD Renal ... Loses - Medications ... - Familial renal ... #Differential #
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Injury (AKI) - Differential ... Abdominal Compartment Syndrome ... , Medications Intra-Renal ... Kidney #Injury #Differential ... #Diagnosis #nephrology
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
hypokalemia and hypomagnesemia ... pump inhibitor - Renal ... Fanconi syndrome ... #Medications #differential ... #diagnosis #nephrology
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Hypokalemia Differential ... oral intake Renal ... loss • Medication ... • Hypomagnesemia ... • Bartter's syndrome
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Hypokalemia - Differential ... K loss • Hypomagnesemia-induced ... hypokalemia • Renal ... #hypokalemia #differential ... algorithm #causes #nephrology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
Causes of Hypomagnesemia ... (steatorrhea) Renal ... Tubulointerstitial renal ... Causes #diagnosis #differential ... #medications #drugs
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hypercalcemia, Hypermagnesemia ... Guillain-Barré syndrome ... Hypocalcemia, Hypomagnesemia ... Testing #Causes #differential ... diagnosis #table #neurology
Approach to Hypomagnesemia 

Fractional excretion of magnesium = (urine magnesium x serum creatinine)/ [0.7 (serum magnesium
Approach to Hypomagnesemia ... cells FEMg >4% = renal ... magnesium loss if renal ... #algorithm #differential ... diagnosis #causes #nephrology
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... - Differential ... Malabsorption RENAL ... • Gitelman's syndrome ... #Low #Causes #Differential