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diagnosis differential oncology adverseeffects algorithm anemia aplastic epidemioliogy falsepositives gap globulin harms heon honc hypereosinophilia management neoplastic platelets primarycare protein
Cancer screening: Do the harms outweigh the benefits? #EBM #epidemioliogy #PubilcHealth #PrimaryCare #HONC #Screening #AdverseEffects #Harms
Cancer screening ... #EBM #epidemioliogy ... PrimaryCare #HONC #Screening ... FalsePositives #BMJ
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... cells - Blood & BM ... • Cytopenia -> BM ... lymphoid organs When Cancer ... #Hematology #Oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... workup, including BM ... • Nonmalignant hematologic ... Malignancy: Metastatic cancer ... Diagnosis #Algorithm #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Toxic injury to BM ... Parvovirus B19 - EBV ... Epstein-Barr virus (EBV ... ) • Leukemia ... Anemia #oncology #hematology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
helminthiasis, cancer ... - Myelogram/BM ... Diagnosis #Signs #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
• Plasma cell leukemia ... acute HIV, HBV, EBV ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... : Lymphoma, Leukemia
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