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diagnosis differential comparison pathophysiology pharmacology serotonin signs symptoms antidepressants bias data evidence hyperthermic hyponatremia inhibitors negativetrials nejm nephrology policy publication
Selective Publication of Antidepressant Trials A more complete picture: contrasting the journal version of antidepressant trials with
trials with the FDA ... NEJMsa065779 #Policy #EBM ... #Psychiatry #NegativeTrials ... Antidepressants #SSRIs ... Bias #Comparison #FDA
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 Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
• Serotonin Syndrome ... Akathisia • SSRI ... Dizziness - Nausea ... sensations) #SSRIs ... #SideEffects #Psychiatry
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Reuptake Inhibitors(SNRIs ... Vomiting Serotonin Syndrome ... gain Incr NE: Nausea ... Dry Mouth #SNRIs ... #SideEffects #Psychiatry
IBS-D Pharmacotherapy Loperamide Rifaximin Eluxadoline Alosetron Antispasmodics Tricyclic antidepressants SSRIs #IBSD #IBS #Diarrhea #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
antidepressants SSRIs ... Irritable #Bowel #Syndrome ... #pharmacology #table
Selective Publication of Antidepressant Trials A more complete picture: contrasting the journal version of antidepressant trials with
trials with the FDA ... NEJMsa065779 #Policy #EBM ... #Psychiatry #NegativeTrials ... Antidepressants #SSRIs ... Bias #Comparison #FDA
Characteristics of Serotonin Syndrome and Other Hyperthermic Syndromes Serotonin Syndrome - SSRIs, second-generation antidepressants, MAOIs, linezolid,
Characteristics of Serotonin Syndrome ... Other Hyperthermic Syndromes ... Serotonin Syndrome ... - SSRIs, second-generation ... Diagnosis #Comparison #Table
Secondary causes of Hypertension • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Secondary causes ... Pseudopheochromocytoma - respond to SSRIs ... Other Endocrine causes ... low renin HTN causes ... #Secondary #causes
Causes of Hyperpyrexia (Temp > 106.7° F) - Differential Diagnosis • Heat Stroke • Drug-induced: Amphetamines,
Causes of Hyperpyrexia ... • Serotonin syndrome ... : SSRIs, MAOIs, ... Differential #Diagnosis #Causes
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
- Cirrhosis Syndrome ... cyclosporine, SSRIs ... Differential #Diagnosis #Table ... #Causes #Sodium
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
treat underlying cause ... cirrhosis, nephrotic syndrome ... Stress, Nausea, ... Meds (Opiates, SSRIs
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