5882 results
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Accuracy Compared - SPEP ... - FLC - UPEP ... Testing #Protein #Diagnosis ... #MGRS #MGUS #SPEP
Diagnostic Testing for Meningitis
History:
 • Triad: Fever, neck stiffness, and altered mental status
 • Sens: 44%
Diagnostic Testing ... + are present; Spec ... if sitting up); Spec ... #Meningitis #diagnosis ... #Specificity #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
SPEP+free light ... monoclonal gammopathy (SPEP ... hypergammaglobulinemia (SPEP ... expensive than SPEP ... testing #workup #diagnosis
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
hypergammaglobulinemia; SPEP ... false- negative SPEP ... Gammopathies #MGUS #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
pathways. 6) SPEP ... monoclonal gammopathy (SPEP ... hypergammaglobulinemia (SPEP ... expensive than SPEP ... disease #workup #diagnosis
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
Electrophoresis (SPEP ... Electrophoresis #SPEP ... #Hematology #Diagnosis
Fungal Biomarkers: Comparing Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 •
Sens ~55-96%, Spec ... Cryptococcus • Sens/Spec ... Galactomannan #diagnosis
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
normal, move on to SPEP ... #differential #diagnosis
Cystic Neoplasms of the Pancreas
 - Serous Cystic Neoplasm
 - Solid Pseudopapillary Tumor (SPT) or Solid
Epithelial Neoplasm (SPEN ... #differential #diagnosis
Summary of Available Tests for Clostridium difficile Infection, in Decreasing Order of Sensitivity
 • Toxigenic culture
culture - Sens High, Spec ... tests - Sens High, Spec ... dehydrogenase - Sens High, Spec ... assay - Sens High, Spec ... CDiff #laboratory #diagnosis