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management antibiotics infant pediatrics risk stepbystep apml differentiation ebm hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis oncology rebelem tls tumor
Validation of the Step-By-Step Approach to Febrile Infants #Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
Infants #Diagnosis ... #StepByStep #Algorithm ... #LP #Antibiotics ... #Risk #Stratification ... #Fever #RebelEM
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... CRP < 20 mg/L #Diagnosis ... #Febrile #Infant ... #LP #Antibiotics ... #Risk #Stratification
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... #LP #Antibiotics ... #Risk #Stratification ... #Fever
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... : - If febrile ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
consideration in febrile ... hyperinflammatory syndrome ... Fever b. ... Treatment Approach ... #Management #Hematology
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