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diagnosis hematology oncology rheumatology acute algorithm classification cvid disorders extravascular hemeonc hemolysis hemolytic hemophagocytic hiv hlh hodgkins hypogammaglobulinemia immunodeficiency immunology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Myelogenous Leukemia • Primary ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... Platelet Disorders - Differential ... changes), high MCV anemia ... unclear, or if a primary ... #Workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... inflammation • Thrombocytopenia ... /Quantity: • Primary ... Causes: - Thrombocytopenia ... - Hemolytic anemia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... usually IgM) (e.g. primary ... #differential # ... #anemia
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
specifically immune thrombocytopenia ... autoimmune hemolytic anemia ... and M panel Management ... DDX - Other causes ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... skin that are caused ... Most common cytopenia ... IDUS) • Immune Thrombocytopenia ... blood count with differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... (NSHL) - (most common ... Immunohistochemical studies (to differentiate ... #oncology #management
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
• Symptoms of primary ... infection - Most common ... enzymes ↑ • Mild anemia ... • Thrombocytopenia ... HIV-1 p24 core Ag
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Diagnosis and Management ... disease of unknown cause ... DIAGNOSIS: • PMR primarily ... • Normocytic anemia ... normal and can help differentiate
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Types of HLH • Primary ... Presentation • Common ... - Cytopenias (anemia ... , thrombocytopenia
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